Prulifloxacin used in medicine

Prulifloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class currently undergoing clinical trials prior to a NDA (New Drug Application) submission to the U.S. Food and Drug Administration (FDA). It is a prodrug which is metabolized in the body to the active compound ulifloxacin. It was developed over two decades ago by Nippon Shinyaku Co. and was patented in November; 1989.In clinical trials in Japan and Italy, prulifloxacin appeared as effective as ciprofloxacin, co-amoxiclav or pefloxacin in the treatment of bronchitis exacerbations or lower urinary tract infections.